17 January, 2012
Volume 22, Issue 1

Volume 22, Issue 1

On the cover: Scanning electron micrograph (contrast-enhanced and colorized using Adobe Photoshop) of the advancing mesendoderm from a Xenopus laevis gastrula. These cells migrate collectively, with monopolar protrusions extending in the direction of travel. Weber et al. show that the coordination of single-cell protrusive and migratory behaviors in this tissue involves mechanically responsive cadherin-based cell cohesion. For more information, see Weber et al., pp. 104–115.

Annotated Table
of Contents

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Impact Factor

The JCR impact factor
for Developmental Cell,
based on papers published
in 2008–2009, and cited
in 2010, was
13.946
© Thomson Reuters Journal Citation Reports (2011)

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Publishing with Cell Press

In the January Issue

Weekly Update

Developmental Cell is now publishing many papers online in advance of the print version of the journal. Here are this week’s articles that are Online Now. To see all of the February issue articles already available, click here.

Ranieri et al. Dual Cos2 phosphorylation sites distinguish high- and low-threshold Hedgehog signaling
Sabine et al. Interplay of mechanotransduction and transcriptional input in lymphatic-valve formation

Issue Highlights

FEATURED ARTICLE

Cell Cycle Control of Centromeres

Cdk1 and Cdk2 activities couple centromeric chromatin propagation to the cell cycle, keeping the CENP-A assembly machinery inactive until the completion of DNA replication and mitosis.

Article by Silva et al.

PERSPECTIVE

Models of Morphogenesis

The fly ovary has yielded several unconventional ways of thinking about planar polarization during epithelial morphogenesis.

Perspective by David Bilder and Saori Haigo

WEB FEATURE

Since we’ve published the last of the 10th anniversary PaperPicks, Dev Cell is now offering authors a new opportunity to provide personal perspectives on their work. Watch for video abstracts (in the same place you would find a graphical abstract) in two articles this month. More will follow...

Article by Megan Andriankaja et al.

Article by Gregory Weber et al.

Video Abstract

Doug DeSimone and colleagues discuss their work on collective cell migration in Xenopus, which shows that cells in the rear orient the leaders to migrate away from them, by using local tugging forces on cadherin cell-cell adhesions to stimulate migratory polarity through recruitment of plakoglobin and reorganization of keratin intermediate filament networks.